• Partial agonist/antagonist of the μ (mu) opioid receptor

  • Long-acting, and therefore is less addictive

  • "Ceiling Effect"- additional dosage does NOT give additional euphoric effects beyond FDA recommended levels, and therefore is less addictive

  • High affinity for the μ (mu) opioid receptor (i.e. out competes other opiates), and therefore carries lower risk for abuse with other opiates

  • Partial agonist element yields anti-craving effect

  •  Typically administered once daily, and therefore yields less behavioral reinforcement for compulsive use


  • Full antagonist of opioid receptor

  • Short acting

  • Primarily used in combination with buprenorphine to prevent misuse (i.e. intraveneous or intranasal administration), but also in the case of opiate overdose response

Buprenorphine/Naloxone Combinations

We will use primarily one of the following three buprenorhpine/naloxone combinations, and of these three we will mostly use suboxone​

  • Bunavail- film strip

  • Suboxone- film strip

  • Zubsolv- tablet

Methadone Versus Buprenorphine

  • Methadone produces more euphoric feelings, and is therefore more addictive

  • Methadone is a full agonist, which means a higher rate of tolerance development

  • Methadone does not have a ceiling effect, and therefore has a greater risk for overdose

  • Methadone use can lead to adverse side-effects such as opioid induced constipation (OIC) and cardiac rhythm disturbance

  • Methadone typically requires daily or nearly daily maintenance at a methadone clinic

"Am I Substituting One Opiate For Another?"

Buprenorphine is different from all other opiates in that it is a partial agonist/antagonist. This yields less craving, less compulsive use, and a less restrictive treatment plan. This helps you live a normal life on your path towards healing and recovery.







Summit Behavioral Wellness
Address: 7601 Hospital Dr [Suite 202], Sacramento, CA 95823
Phone: (916) 689-1062                      email: contact@summitbewell.org